# DSIP reading list

> Arizona Vitality Clinics reading list — The Arizona Vitality Clinics reading list includes the DSIP insomnia experiment, rabbit sleep studies and human hormone and sleep-onset findings.

**Reading list**

The small insomnia experiment starts the question. The sleep-onset and hormone papers make it harder to answer.

## The opening experiment

The [human insomnia experiment](https://pubmed.ncbi.nlm.nih.gov/7028502/) is the starting point for the morning question. For the most unexpected change of direction, I would turn next to the [fall in circulating DSIP-like material as sleep began](https://pubmed.ncbi.nlm.nih.gov/8745061/).

The [2006 review](https://pubmed.ncbi.nlm.nih.gov/16539679/) supplies the sharpest challenge to the broad sleep claim. The rabbit, bed-rest and hormone papers below fill out the disagreements and the particular experimental settings. The list includes animal and isolated-tissue work as well as human studies; each essay identifies which kind of experiment it is discussing.

## References

[1] The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep https://pubmed.ncbi.nlm.nih.gov/7028502/
[2] Delta sleep-inducing peptide (DSIP): a still unresolved riddle https://pubmed.ncbi.nlm.nih.gov/16539679/
[3] Characterization of a delta-electroencephalogram (-sleep)-inducing peptide https://pubmed.ncbi.nlm.nih.gov/265572/
[4] [Hypnogenic properties of DSIP peptide analogs: structural-functional relationship] https://pubmed.ncbi.nlm.nih.gov/11525128/
[5] Human plasma DSIP decreases at the initiation of sleep at different circadian times https://pubmed.ncbi.nlm.nih.gov/8745061/
[6] Plasma concentration of nine hormones and neurotransmitters during usual activities or constant bed rest for 34 H https://pubmed.ncbi.nlm.nih.gov/7895296/
[7] Decreased delta-sleep and plasma delta-sleep-inducing peptide in patients with Cushing syndrome https://pubmed.ncbi.nlm.nih.gov/7700506/
[8] Reduction of immunoreactive ACTH in plasma following intravenous injection of delta sleep-inducing peptide in man https://pubmed.ncbi.nlm.nih.gov/2554357/
[9] Different effects of delta-sleep-inducing peptide on arginine-vasopressin and ACTH secretion in normal men https://pubmed.ncbi.nlm.nih.gov/7698722/
[10] Delta-sleep-inducing peptide (DSIP) inhibited CRF-induced ACTH secretion from rat anterior pituitary gland in vitro https://pubmed.ncbi.nlm.nih.gov/3017833/
[11] Delta-sleep-inducing peptide sequels in the mechanisms of resistance to emotional stress https://pubmed.ncbi.nlm.nih.gov/8597403/

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At Arizona Vitality Clinics I pore over published research on sleep and waking; the site is an essay collection, not a business, and offers no medical advice.